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Recent news

May 20, 2010
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Dr. Ana Lukic gives presentation on pipelineMAX technology at Neurotech 2010 Conference.

April 27, 2010
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Predictek & RTH Corp awarded Phase II SBIR grant from the U.S. Navy to employ advanced imaging technology to design custom hearing protection.

April 22, 2010
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Pfizer commissions Predictek to perform neuroimaging data analysis for a recent drug study in neuroscience research.

March 12, 2010
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Predictek, Inc., and Abiant, Inc., form new joint venture to develop diagnostic for Alzheimer's disease and other dementias based on Predictek's pipelineMAX technology.

 


Publications
Our team has published hundreds of papers in academic peer-reviewed journals. The following is a list of a few of our publications in key areas.
-Neuroimaging / fMRI
-PET & SPECT
-Ophthalmic imaging
-Image analysis / machine learning / pattern recognition
-X-ray imaging


Neuroimaging / fMRI
- Zhang J, Liang L, Anderson JR, Gatewood L, Rottenberg DA, Strother SC. A java-based fMRI processing pipeline evaluation system for assessment of univariate general linear model and multivariate canonical variate analysis-based pipelines. Neuroinformatics (in press).
- Lukic AS, Wernick MN, Tzikas DG, Chen X, Likas A, Galatanos NP, Yang Y, Zhao F, Strother SC. (2007): Kernel methods for analysis of functional neuroimages. IEEE Trans Med Imaging 26(12):1613-1624. [PubMed]
- Zhang J, Liang L, Anderson JR, Gatewood L, Rottenberg DA, Strother SC. Evaluation and Comparison of GLM- and CVA-based fMRI Processing Pipelines with Java-based fMRI Processing Pipeline Evaluation System. Neuroimage (in press).
- Zhang J, Anderson JR, Liang L, Pulapura SK, Gatewood L, Rottenberg DA, Strother SC. Evaluation and Optimization of fMRI Single-Subject Processing Pipelines with NPAIRS and 2nd-level CVA. Magnetic Resonance in Medicine (in press)
- Lukic AS, Wernick MN, Yang Y, Hansen LK, Arfanakis K, Strother SC. Effect of spatial alignment transformations in PCA and ICA of functional neuroimages. IEEE Trans Med Imaging 26(8):1058-68, 2007. [PubMed]
- Lukic AS, Wernick M N , Strother SC. (2007) Evaluation of methods for detection of brain activations from functional neuroimages,” Artificial Intelligence in Medicine (invited for special issue) 25: 69-88. [PubMed]
- Kustra R, Strother SC. (2001): Penalized discriminant analysis of [15O]-water PET brain images with prediction error selection of smoothness and regularization hyperparameters. IEEE Trans Med Imaging 20(5):376-87. [PubMed]
- Strother SC, Anderson J, Hansen LK, Kjems U, Kustra R, Sidtis J, Frutiger S, Muley S, LaConte S, Rottenberg D. (2002): The quantitative evaluation of functional neuroimaging experiments: the NPAIRS data analysis framework. Neuroimage 15(4):747-71. [PubMed]

- Shaw ME, Strother SC, Gavrilescu M, Podzebenko K, Waites A, Watson J, Anderson J, Jackson G, Egan G. (2003): Evaluating subject specific preprocessing choices in multisubject fMRI data sets using data-driven performance metrics. Neuroimage 19(3):988-1001. [PubMed]
- LaConte S, Anderson J, Muley S, Ashe J, Frutiger S, Rehm K, Hansen LK, Yacoub E, Hu X, Rottenberg D and others. (2003): The evaluation of preprocessing choices in single-subject BOLD fMRI using NPAIRS performance metrics. Neuroimage 18(1):10-27. [PubMed]
- Strother SC, La Conte S, Kai Hansen L, Anderson J, Zhang J, Pulapura S, Rottenberg D. (2004): Optimizing the fMRI data-processing pipeline using prediction and reproducibility performance metrics: I. A preliminary group analysis. Neuroimage 23 Suppl 1:S196-207. [PubMed]
- Strother SC. (2006): Evaluating fMRI preprocessing pipelines. IEEE Eng Med Biol Mag 25(2):27-41. [PubMed]
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PET & SPECT
- Miles N. Wernick and John N. Aarsvold, eds., Emission Tomography: The Engineering and Physics of PET and SPECT, San Diego: Academic Press, 2004, pp. 596.
- Kustra R, Strother SC. (2001): Penalized discriminant analysis of [15O]-water PET brain images with prediction error selection of smoothness and regularization hyperparameters. IEEE Trans Med Imaging 20(5):376-87. [PubMed]
- Miles N. Wernick, E. James Infusino, and Milos Milosevic, “Fast spatio-temporal image reconstruction for dynamic PET,” IEEE Transactions on Medical Imaging, vol. 18, pp. 185-195, March 1999.
- Chien-Min Kao, Jeffrey T. Yap, Jogeshwar Mukherjee, and Miles N. Wernick, “Image reconstruction for dynamic PET based on low-order approximation and restoration of the sinogram,” IEEE Transactions on Medical Imaging, vol. 16, pp. 738-749, 1997.
- Bing Feng, P. Hendrik Pretorius, Troy Farncombe, Seth. T. Dahlberg, Manoj V. Narayanan, Anna M. Celler, Jeffrey A. Leppo and Michael A. King, “Simultaneous assessment of cardiac perfusion and function using 5-dimensional imaging with Tc-99m teboroxime,” Journal of Nuclear Cardiology, vol. 13, pp. 354-361, 2006.
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Ophthalmic imaging
- Elzie C. Chan, Daniel K. Roberts, Donald D. Loconte, and Miles N. Wernick, “Digital camera system to perform infrared photography of iris transillumination,” Journal of Glaucoma, vol. 11, pp. 426-428, 2002.
- Daniel K. Roberts and Miles N. Wernick, “Infrared imaging technique can help prove the diagnosis of pigment dispersion syndrome in blacks who do not show iris transillumination defects via traditional methods,” Journal of Glaucoma, 2007 (in press).

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Image analysis / machine learning / pattern recognition
- Ahmad Abu Naser, Nikolas P. Galatsanos, and Miles N. Wernick, “Methods of detecting objects in photon-limited images,” Journal of the Optical Society of America A, in press, 2005.
- Liyang Wei, Yongyi Yang, Robert M. Nishikawa, and Miles N. Wernick, “Relevance vector machine for automatic detection of clustered microcalcifications,” IEEE Transactions on Medical Imaging, in press, 2005.
- Issam El-Naqa, Yongyi Yang, and Miles N. Wernick, “A support vector machine approach for detection of microcalcifications,” IEEE Transactions on Medical Imaging, vol. 21, no. 12, pp. 1552-1563, 2002.
- Ahmad Abu-Naser, Nikolas P. Galatsanos, Miles N. Wernick, and Dan Schonfeld, “Object recognition based on impulse restoration using an expectation-maximization algorithm,” Journal of the Optical Society of America A, vol. 15, pp. 2327-2340, 1998.
- Miles N. Wernick, “Pattern classification by convex analysis,” Journal of the Optical Society of America A, vol. 8, pp. 1874-1880, 1991.
- Miles N. Wernick and G. Michael Morris, “Image classification at low light levels,” Journal of the Optical Society of America A, vol. 3, pp. 2179-2187, 1986.
- G. Michael Morris, Miles N. Wernick, and Thomas A. Isberg, “Image correlation at low light levels,” Optics Letters, vol. 10, pp. 315-317, 1985.
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X-ray imaging
- C. Muehleman, J. Li, M. Wernick, J. Brankov, K. Kuettner, and Z. Zhong, “Yes, you can see cartilage with X-rays: Diffraction enhanced X-ray imaging for soft and hard tissues,” Journal of Musculoskeletal and Neuronal Interactions, vol. 4, pp. 369-370, 2004.
- Miles N. Wernick, Jovan G. Brankov, and Alejandro Saiz-Herranz, “Noise analysis and image denoising for DEI,” Proceedings of SPIE, vol. 5535, pp. 660-667, 2005.
- Miles N. Wernick, J. G. Brankov, D. Chapman, Y. Yang, E. Pisano, C. Parham, C. Muehleman, Z. Zhong, M. A. Anastasio, “Multiple-image radiography and computed tomography,” Proceedings of SPIE, vol. 5535, pp. 369-379, 2005.
- Miles N. Wernick, Oliver Wirjadi, Dean Chapman, Zhong Zhong, Nikolas P. Galatsanos, Yongyi Yang, Jovan G. Brankov, Oral Oltulu, Mark A. Anastasio, and Carol Muehleman, "Multiple-image radiography," Physics in Medicine and Biology, vol. 48, pp. 3875-3895, 2003.
- Oral Oltulu, Zhong Zhong, Moumen Hasnah, Miles N. Wernick, and Dean Chapman, “Extraction of extinction, refraction and absorption properties in diffraction enhanced imaging,” Journal of Physics D: Applied Physics, vol. 36, pp. 2152-2156, 2003.

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